Much ado about the Covid ‘second wave’

please note: events of the past weeks of December have shown the speculation surrounding the so-called ‘seasonal thesis’ below to be completely wrong, instead we have a witnessed another surge as the result the rise of a more infectious lineage of the virus, the article is preserved here to serve as a record of this open speculation.

TWO WEEKS ago Boris Johnson announced a second nation-wide lockdown for the UK. This apparently after data showing projected infection increases, outstripping the capacity of the NHI — there is a broad variance shown by the conflicting mathematical models, which do not take into account exposure to UV radiation.

As the Northern economies enter Winter, the ‘second wave is upon us’. However the same cannot be inferred by local data. So far as the South is concerned, summertime is proving that when it comes to Covid-19 every indication points to the pandemic being seasonal, and that a diverging UV profile will lesson the impact in the South.

The announcement of a vaccine with a 90% effectiveness has boosted hopes for an end to the pandemic. With Nelson Mandela Bay metropole the sole outlier, South Africa has been spared the worst ravages of the ‘second outbreak’. The nation has an extraordinary high recovery rate and most early projections have proven wrong, witness the controversy over the modelling.

‘In the South African context, there is close to zero value in going back to a hard lockdown as it is not going to achieve anything different in controlling the epidemic’ is the view of Professor Shabir Madhi from the school of pathology at the University of the Witwatersrand. This stands in contrast to Dr Zweli Mkhize’s insistence that his mathematical models are correct.

What is not being said by either sides, (and speaking as an environmentalist) is that there are very different environmental factors at play in Africa. Not only do we have a different seasonal procession, with the South experiencing Summer when North experiences Winter, but there are vastly different weather patterns, all of which impacts on the amount of sunshine and consequently UV radiation experienced by the average individual.

South Africa’s UV burn index is amongst the highest in the world. Bare in the mind that the coronovirus is a derivative of the common cold, and operates much in the same way that the flu does, save for the fact that coronoviruses tend to break out in clusters unlike the flu which comes in waves. Direct normal radiation for Upington for example, is nearly 1000 w/m2, and vastly different from our coastline.

The whole notion of a ‘second wave’ for the entire world, is potentially a flawed assumption made by the World Health Organisation which has tended to operate as if the earth were flat in the process dishing out advice that is no better than that given by socialist bureaucrats during the Soviet Union.

The mandarins and technocrats in Geneva simply rolled out policies for the entire world this year, a one-size-fits-all determination that treats every economy as if we are all living in Alaska, and which deserves to be tested and scrutinised by local and regional scientific councils.

The only ones benefiting from this extraordinary overreach, are the large pharmaceutical companies which stand to make a mint out of the supply of PPE and the much-vaunted vaccine. A vaccine which may take anywhere up to 5 -7 years to dispense. Nevetheless questioning Covid stats, may incur professional liability and institutional sanctions much in the same way that questioning received doctrine on the HIV epidemic has become a shibboleth of notable proportion.

Now more than ever, is the time to host a national symposium on what is known about the virus within the local context, what still needs to be understood and to derive policies based upon evidence-based science and empirical research rather than policy decisions made externally and consequently adopted by our government without any forethought as to the consequences.

Unfortunately as the HIV crisis has shown, the likelihood of the South African government taking a lead where science is concerned is extremely slim. Read my piece on Skepticism during the Mbeki era.

A vaccine is just the beginning of the fight against Covid-19 …

THIS PAST week saw British scientists lauded for a successful phase 1 vaccine trial. A working vaccine may be available by the end of 2020. Unfortunately deploying a global immunisation programme may prove to be harder than producing the vaccine.

Although the United Nations is pushing all countries to join ‘an effort to make vaccines and drugs to fight Covid-19 cheap enough that the poorest populations in the world can be treated’, the sheer scale of such an endeavour looks daunting.

South Africa with a population of 58.8 million would require production of at least 160 000 doses per day for over a year to cover the entire country. Dispensing the vaccine would require 6712 jabs per hour to complete in 12 months, a Promethean task, more likely to occur over 5 to 10 years.

In other words, while the good news is that the world has a working vaccine, one of several vaccines capable of producing the right antibodies and killer T cells required to defend against the virus, the logistical problems of immunisation, make the pandemic likely to stay with us for the foreseeable future.

Technological innovation such as robotic application and drone delivery, novel production techniques and other medical advances, could bring this horizon closer — the day when everyone has immunity and countermeasures such as masks, social distancing and other measures are no longer required.

Bare in mind that as more people recover and gain natural immunity, the target population for an immunisation programme is lowered, thereby reducing the immediate task at hand. Although there is some debate as to whether or not, such immunity is short term and may fall off over time.

By that stage, those who would have died from the virus, will in most likely be dead. The risks of cluster outbreaks and casualty ward spikes will have diminished, and the burden on our health system will normalise along with the impact on the economy.

In effect, the virus and its grip on society, will have weakened, at least for now, but the risk of future flare-ups and other coronovirus clades remain.

Targeted immunisation programmes focusing on vulnerable groups and maximising scarce resources could also assist us in meeting our goal. But for now, we stuck with the ‘no longer novel’ coronovirus of 2019, which looks set to become as prevalent as the common cold, and a seasonal disease just like the flu.

Dear Mr President, the paradox of leadership during Covid-19

THERE is a paradox in philosophy, one popularly referred to as Buridan’s Ass. It tells the story of a donkey that is equally hungry and thirsty, and placed precisely midway between a stack of hay and a pail of water. The paradox assumes the ass will always go to whichever is closer, and therefore it dies of both hunger and thirst since it cannot make any rational decision between the hay and water.

Similarly, South Africa is caught between two seemingly contradictory paths, both of which necessitate immediate and urgent action.

On the one hand, we are required to combat a ‘killer virus’, a virus whose impact upon our health and the health of our broader population is only beginning to be understood. If we do nothing, we risk inundating our health care system with casualties, and incurring unacceptable loss of life.

On the other hand, we are dependent upon our economy, for our livelihoods and way of life. Not simply our lives, but the very manner — both way and means by which we as individual households, survive year to year. We are all stricken by the need to feed and clothe our families, forced to pay our way, our rent and our bills. It matters not whether one believes necessities of life exclude alcohol or the nails one uses to repair ones roof, or whether we do depend upon smokes or the tools one uses to fix ones walls.

If we cease to engage with our economic imperatives, we also risk death — incurring unacceptable, diminished living standards, shortened life spans and negative health outcomes as we move forward.

That the burden of disease is also the burden of hunger, has already been written about here at length, and only a fool would suggest otherwise, to engage in a binary debate between people’s lives and livelihoods. Both are equally important.

The conundrum is similar to a patient forced to take medication. The list of side-effects may turn out to be worse than the disease. The cure may kill us all.

To complicate matters, there are urgent human rights and serious civil freedom predicaments that have compounded the situation. What appears to be nothing less than a silent coup, occurring the world over, a creeping Global Police State and a major shift in national and international imperatives.

Bar the health agenda, it is with almost zero constitutional backing that our own government has embarked upon a drastic course of action, (taken alongside other governments both across the continent and the world), with outcomes that appear to result in a blatant seizure of power in favour of the national executive.

Power taken without debate, taken away from Parliament in favour of the Executive, power usurped from the Courts, without checks and balances in favour of a centralised authority, the so-called National Command Council (NCC). The erosion of democratic institutions which have characterised our republic for decades and likewise many other democracies, is further reflected in local authorities pulling away from democratic norms and standards .

That the Independent Police Investigative Directorate (Ipid) in South Africa has admitted it was an “error of law” on its part not to investigate the alleged role played by the Johannesburg Metro Police in the death of Collins Khoza at the hands of the SANDF is to be welcomed.

But a lot more needs to be done to preserve the rule of law in our country.

For starters, recognition that the SANDF may only act in an adjunct or auxiliary role to the Police during a National Disaster — the courts and justice system must be seen as primary during such a difficult period, especially one where the metaphor of war is easily bandied about, but where no actual war has been declared. Even then, we are a democracy and expect the democratic will and rule of law to prevail.

There are troubling signs that local authorities also wish to curtail rights not to be subject to search and seizure without a warrant.

The lock-down certainly has a sell-by-date and it is surely an extraordinary act of chicanery for us to believe that powers emanating from a piece of legislation designed primarily to deal with natural disasters such as hurricanes, drought, famine and earthquakes is fit for the purpose of public health initiatives taken over the past month?

Parliament must return to its civic duties, and the justice system must resume its oversight role. The many rules, bylaws and regulations must be debated by our elected representatives, and the NCC must explain why it is that they find themselves unable to choose between a stack of hay and a bucket of water, unable to speak to the absence of a vaccine and the problematic of herd immunity, unable to come through for those who demand alcohol or tobacco? Stricken as it were, by the enormity of what they have done, in seizing power over the commons.

Covid-19 Anti-Vaxers stage a comeback, but fail to check facts

IT STARTED with an interview on Al Jazeera, some brazen French researchers making shocking off-the-cuff remarks about a study on the potential use of the BCG vaccine against COVID-19 in Africa. Taken at face value, it appeared that the French were once again conducting openly racist, TB vaccine experiments in their former colonies. That’s TB as in Tuberculosis.

The story quickly escalated and amplified into a headline grabbing: ‘Senator Wetangu’la calls on African leaders to reject COVID-19 vaccine test on continent‘. As journalists failed to check if what was being said was relevant or even true. The French embassy was moved to caution that the researcher’s opinions “do not reflect the position of the French authorities.

By Sunday, Anti-Vaxers were having a field day on twitter, but hadn’t bothered to check the facts. Yes, Covid-19 Vaccine trials are being conducted on EVERY continent, not just our own,

The first was a Phase 1 clinical trial evaluating an ‘investigational vaccine designed to protect against coronavirus disease 2019 (COVID-19)’ begun at Kaiser Permanente Washington Health Research Institute (KPWHRI) in Seattle, USA.

Phase 1 trials involve testing of drugs or vaccines on healthy volunteers for safety, and  also testing multiple doses (dose-ranging). Most countries such as South Africa have regulatory checks in place to avoid citizens becoming unwitting participants to phase 1 trials.

Our Constitution specifically outlaws such experimentation and states under Article 12  (2) Everyone has the right to bodily and psychological integrity, which includes the right— (a) to make decisions concerning reproduction; (b) to security in and control over their body; and (c) not to be subjected to medical or scientific experiments without their informed consent. 

Trials of Covid-19 related vaccines have already been conducted in Japan and elsewhere.

Large scale global trials involving patients from Argentina to Thailand under the auspices of the WHO are already underway.

There appears to be some confusion as to what a vaccine does, as opposed to antiviral treatment for COVID-19.  Ekurhuleni mayor, Mzwandile Masina, recently proposed using the municipality’s emergency funds “to procure the vaccine Inferon B from Cuba”, a proposal debunked by Africa Check.

The possibility that South Africa will also receive an actual trial vaccine is a big deal, not because we are likely to become lab rats, but because citizens will hopefully be able to volunteer for the phase 1 trials to assess the effectiveness of the vaccine in creating antibodies to the virus — a therapy which could prove to be a game-changer in the global pandemic.

As with any new drug or therapy, there will always be safety concerns, but the alternative is to live with permanent lock-downs and quarantines.

I would rather just get a jab in the arm thanks.

UPDATE: News24 forced to retract inaccurate coronovirus vaccine story